**Providing a framework for treating substance use disorders (SUDs) in office-based psychotherapy, the second edition of this trusted work has been updated throughout and features two entirely new chapters.** The authors show how clinicians from any background can leverage the therapeutic skills they already have to address clients’ alcohol and drug problems competently and effectively. Vivid case examples demonstrate ways to engage clients at different stages of change; set collaborative treatment goals; address SUDs concurrently with other psychological problems; and interweave motivational, cognitive-behavioral, and other interventions, tailored to each individual’s needs. Reproducible forms and handouts can be downloaded and printed in a convenient 8 1/2 x 11 size. New to This Edition *Chapter on evidence-based principles and interventions. *Chapter on moderation-focused alcohol treatment. *Revised throughout with current data, clinical techniques, and examples. *Reflects over 15 years of important changes in the fieldincreased demand for integrated treatment, the ongoing opioid crisis, the growth of harm reduction and medication-assisted treatments, and more.