**A spirited biography of the prophetic and sympathetic philosopher who, along with Voltaire and Rousseau, helped build the foundations of the modern world.** Denis Diderot is often associated with the decades-long battle to bring the world’s first comprehensive *Encyclop�die* into existence. But his most daring writing took place in the shadows. Thrown into prison for his atheism in 1749, Diderot decided to reserve his best books for posterity–for us, in fact. In the astonishing cache of unpublished writings left behind after his death, Diderot dreamed of natural selection before Darwin, the Oedipus complex before Freud, and genetic manipulation centuries before Dolly the Sheep. Even more audaciously, the writer challenged virtually all of his century’s accepted truths, from the sanctity of monarchy, to the racial justification of the slave trade, to the complications of human sexuality. One of Diderot’s most attentive readers during his lifetime was Catherine the Great, who not only supported him financially, but invited him to St. Petersburg to talk about art and help her think about reforming her empire. In this thematically organized biography, Andrew S. Curran vividly describes Diderot’s tormented relationship with Rousseau, his curious correspondence with Voltaire, his passionate affairs, and his often paradoxical stand on art, morality, politics, and religion. But what this book brings out most brilliantly is how the writer’s self-doubts were an essential part of his genius and his ability to flaunt taboos, dogma, and convention.